Frequency of Polymorphism Alu Insertion in Progesterone Receptor Gene in Endometriosis
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Abstract:
Background and Aims: This research aimed to study a possible link between endometriosis and polymorphism of the progesterone receptor gene. Materials and Methods: The control group consisted of 86 women without endometriosis and the case group comprised 86 patients with a diagnosis of endometriosis by laparoscopy. Genotypes for Alu insertion polymorphisms (A1/A1, A1/A2 and A2/A2) were described by polymerase chain reaction and determined on a 2% agarousegel. Results: The genotype frequencies of A1/A2 and A2/A2 were not significantly higher in patients than in the control group without endometriosis. On the other hand differences in the Alu insertion polymorphism frequencies were not significant. Conclusion: According to our investigations, we conclude that there is not a significant correlation between Alu insertion polymorphism and endometriosis. ;line-height:115%'> According to our investigations, we conclude that there is not a significant correlation between Alu insertion polymorphism and endometriosis.
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Journal title
volume 3 issue 3
pages 185- 190
publication date 2016-08
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